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Risk Factors
Causes and Risk Factors
Aside from a known association with exposure to vinyl chloride, there are no known chemical or environmental
agents that lead to the development of brain tumors.
Some types of brain cancer are more likely to develop when tumor suppressor genes
(genes that prevent the growth of cancerous cells) are genetically altered or deleted.
. Inherited diseases that are associated with brain tumors
include the following:
- Multiple endocrine neoplasia type 1 (pituitary adenoma)
- Neurofibromatosis type 2 (brain and spinal cord tumors)
- Retinoblastoma (malignant retinal glioma)
- Tuberous sclerosis (primary brain tumors)
- Von Hippel-Lindau disease (retinal tumor, CNS tumors)
Patients with a history of melanoma, lung,breast , colon, or
kidney cancer are at risk for secondary brain cancer.
Exposure to vinyl chloride is an environmental risk factor for brain cancer. Vinyl chloride is a carcinogen, that is, a cancer-causing substance. It is used in manufacturing plastic products
such as pipes, wire coatings, furniture, car parts, and housewares, and is present in tobacco smoke.
Vinyl chloride can seep into the environment as a result of incorrect disposal, and it can also be released into the air or
water by manufacturing and chemical plants. The risk of developing brain cancer is higher for those who reside near these plants or work there.