Name
GLOMERULONEPHRITIS,ACUTE ( POST STREPTOCOCCAL )
DESCRIPTION
DETAIL
OTHER TESTS : * SERUM C3 LEVELS & CH-50 LEVELS - DEPRESSED IN 90% CASES * ANTI GLOMERULAR BASEMENT MEMBRANE ANTIBODY - PRESENT * ANTI NEUTROPHIL CYTOPLASMIC ANTIBODY - PRESENT * URINE - HAEMATURIA, RED BLOOD CELL CAST, PROTEINURIA, WBCS & OCCASIONALLY WBC CAST. * SERUM CREATININE - NEAR NORMAL
TYPENOTES
Medical Care: Treatment of acute PSGN is mainly supportive because there is no specific therapy for renal disease. Treat the underlying infections when acute GN is associated with chronic infections. " Antimicrobial therapy o Antibiotics (eg, penicillin) are used to control local symptoms and to prevent spread of infection to close contacts. o Antimicrobial therapy does not appear to prevent the development of GN, except if given within the first 36 hours. " Loop diuretic therapy o Loop diuretics may be required in patients who are edematous and hypertensive in order to remove excess fluid and to correct hypertension. o Relieves edema and controls volume, thereby helping to control volume-related elevation in BP. o Vasodilator drugs (eg, nitroprusside, nifedipine, hydralazine, diazoxide) may be used if severe hypertension or encephalopathy is present. o Glucocorticoids and cytotoxic agents are of no value, except in severe cases of PSGN. Diet: " Sodium and fluid restriction - For treatment of signs and symptoms of fluid retention (eg, edema, pulmonary edema) " Protein restriction for azotemic patients - If no evidence of malnutrition Activity: Recommend bed rest until signs of glomerular inflammation and circulatory congestion subside. Prolonged inactivity does not benefit in the patient recovery process.
RELATED DISEASE
Not Available Disease
DISEASE
INVESTIGATION
BLOOD UREA, SERUM CREATININE, URINE ROUTINE, BUN, COMPLETE BLOOD COUNT