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Prostate Cancer - New Genetic Risk Factors
London, Feb 11 (ANI): British and Australian scientists have achieved a major genetic breakthrough in
the understanding of prostate cancer, paving the way
for new tests and treatments for the disease.
The scientists say that they have found seven new sites in the human genome that are linked to a manβs
risk of developing prostate cancer.
According to them, their discovery may pave the way for treatments targeting specific genes, and a
much-needed screening test for the disease.
The scientists say that each of the genetic alterations their latest study has revealed may increase
a manβs chances of developing prostate cancer by up
to 60 per cent.
Although they called their findings exciting, they clarified that more research was needed before
they were translated into benefits for patients.
A group of scientists led by Dr. Ros Eeles examined the genetic makeup of more than 10,000
men as part of the study, which was supported by Cancer Research UK.
The scientists came to the conclusion that a gene known as MSMB could be used in prostate
prostate cancer
screening and disease monitoring The scientists came to the conclusion that a gene known as MSMB
could be used in prostate cancer screening and disease monitoring based on their observations.
They also discovered a different region of the genome that contains the gene LMTK2, which might
serve as a brand-new therapeutic target.
The development of prostate cancer is thought to be influenced by a variety of factors, and
certain gene combinations may significantly contribute to the disease, according to scientists.
The new study, according to the research team, contains the greatest number of genetic
risk factors forprostate cancer to date.
These encouraging findings could improve targeted screening and treatment as well as help us
determine the risk of developing prostate prostate cancer
more precisely. The Scotsman quoted Eeles as
saying in Nature Genetics that genetic profiling would actually target who should receive screening
and what kind of care they should receive.
Professor Doug Easton, director of Cancer Research UKβs genetic epidemiology unit at the University of
Cambridge, said: βIn comparison with other cancers,
such as breast and
lung cancer, we understand little about how
prostate cancer develops. These results will greatly improve our knowledge of this important disease.
The new research would improve our understanding of the condition, but Dr. Chris Hiley, from the prostate
cancer charity, cautioned that it might take some time before any practical benefits appeared.