Monograph: |
Becaplermin
Drug Profile
Becaplermin is a platelet-derived growth factor that enhances the formation of granulation tissue and promotes wound healing . Becaplermin is applied topically as a 0.01% gel in the management of neuropathic diabetic skin ulcers (see Diabetic Complications). It is applied once daily, covered by a moist saline gauze dressing, for up to 20 weeks. If no meaningful healing process is evident after 10 weeks of therapy, treatment should be re-assessed.
Becaplermin should not be applied to ulcers where neoplasms are present or to clinically infected ulcers. If the ulcer becomes infected during therapy, becaplermin should be stopped until the infection has cleared.
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