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Carbetocin
Carbetocin is a synthetic analogue of oxytocin reported to have a longer duration of action. For the prevention of uterine atony and excessive bleeding after caesarean section under epidural or spinal anaesthesia, a single dose of 100 micrograms may be given by slow intravenous injection over 1 minute. Carbetocin must only be given after delivery of the infant, preferably before removal of the placenta.
Breast feeding.
In 5 women who were 7 to 14 weeks postpartum, carbetocin was measured in the breast milk within 90 minutes of a single 70-microgram intramuscular dose.The ratio of milk to plasma concentrations was low, suggesting that very little carbetocin was distributed into breast milk. The American Academy of Pediatrics considers that the use of carbetocin is usually compatible with breast feeding
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